Feeling fatigued after prostate cancer treatment

Have you been feeling downright exhausted, tired and spent? Mentally and physically? That’s probably fatigue talking.

What exactly
is fatigue?

Everyone describes it a bit differently. Some men say they are dog-tired, drained or weary all the time. Others say they're completely knackered and exhausted most of the day.

The key difference is that fatigue goes beyond occasional tiredness. It’s like your energy has been completely zapped — making it harder to sleep, work, or hang out with friends and family. Fatigue can have a draining

. It's not usually the kind of sleepiness that you can push through by getting a good night of sleep, or with a cup of coffee. This feeling of being drained can linger for a long time, sometimes even months or years. Simply just being tired, on the other hand, usually goes away after resting up a bit.

People describe this type of fatigue as ‘whole-body tiredness’.

How common is fatigue during prostate cancer?

Almost everyone diagnosed with cancer experiences fatigue, as cancer itself is a lot on the body. Fatigue is so common, that about 3 in 4 men with prostate cancer go through it.

What causes excessive tiredness?

It’s tricky because a number of things can bring on fatigue when you're going through prostate cancer treatment.

With prostate cancer, it’s common to feel worn down due to:

  • not having enough sleep or rest

  • eating poorly and not getting the right amount of exercise

  • stress, anxiety, or depression

  • aches and pains from treatment

  • body or hormonal changes from treatment

Take time to listen to your body and better understand where your exhaustion may be coming from. Work with your doctor or care team to understand what you can expect before, during and after treatment and how to best manage your energy supply going forward.

How do certain prostate cancer
treatments bring on fatigue?

Treatment can have a large impact on your body and mind, and just might be the reason why you feel exhausted.

All prostate cancer treatments can cause fatigue, but some can make it worse:

  • chemotherapy

  • hormone therapy

  • radiation therapy

  • more than one treatment at the same time

What can you do to
pump up your energy?

before, during and after treatment is key. with an exercise program could also help improve your energy levels more quickly. To help you get going, talk to your doctor or care team about having a nutrition and workout plan created that will work just for you.

Below, read more on how each treatment can take its toll.

Hormone Therapy

There are many types of

Depending on which kind you have, and how long you’re on it, the fatigue can vary.

Short term:
If you’re on hormone therapy for a few months, you might find the fatigue gets better soon after treatment.

Long term:
If you’re on hormone therapy for a while, and the fatigue is hard to deal with, talk to your doctor. You may be able to take a break from therapy if the cancer isn’t growing. This break will give you a chance to lessen the fatigue effects and get some relief.

Hormone therapy can also affect your everyday abilities and desire to move around. It’s important to work through it and stay physically active, to keep up your strength. Proper rest, nutrition and exercise will also be key — according to your doctor or care team’s guidelines.



your energy levels will probably be up and down. Your doctor will tell you how many rounds of chemo you’ll have, and how many weeks your sessions will last, but fatigue can make this time challenging. As you have more sessions, the fatigue can start to feel worse.

But after finishing a whole course of chemotherapy, most men find their energy levels improve. Even with this improvement, however, it can feel like the fatigue is lingering on for a while.

Surgery (radical prostatectomy)


you might be exhausted and not in the mood to move around. And that’s completely understandable — your body’s just been through a lot.

To help you heal faster, and to reduce fatigue, your doctor or care team will probably want you doing some light activity, like walking, soon after surgery. Moving can give you an energy boost, keep your mind active and also help with constipation. Constipation (not being able to poop easily or empty your bowels) is uncomfortable and can be stressful for your body.

After surgery, fatigue can last a few weeks or even a bit longer.

Radiation therapy

Both types of

(external beam radiation and brachytherapy) can cause fatigue. Those tired and drained feelings can start while you’re getting therapy but sometimes it doesn’t happen until afterwards.

Some men find it lasts for weeks but it can go on for months.

High-Intensity Focused Ultrasound (HIFU) and Cryotherapy

and are shorter treatments that can both cause some level of fatigue. After the procedure, you might feel tired after but you should soon get back to normal energy levels. Check with your doctor for more details.


Different types of

can leave you very tired afterwards. They can also make you feel sick to your stomach and feel like you need to throw up. Staying hydrated and getting enough rest is critical.

Active Surveillance

People on

often don’t have many physical problems — but they may still deal with anxiety, stress and depression. These issues can make it harder to stay active and take care of yourself — and put you at risk for fatigue. If you’re feeling exhausted all the time, it’s also possible there’s something else going on. Talk to your doctor about fatigue and what you can do to regain energy.

Watchful Waiting

On its own,

does not cause fatigue.
Since the cancer isn’t being actively treated, your body is not being put through the stresses of treatment or recovery. Still, cancer itself can bring about stress, anxiety and depression, making it tough to eat well, feel rested and keep up your energy.

Talk to your doctor or
care team about fatigue

If you’ve been feeling excessively tired, whether physically or emotionally, let your doctor or care team know. They can guide you towards getting proper rest, and any other help you may need.

What's next?

Now that you've read up on Feeling fatigued after prostate cancer treatment , here are some related articles to explore as you continue to build your knowledge and understanding of this topic.
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